For a 2x4 module to be altered frequently, how about a suspended ceiling tile? I have part of one I've been using as a portable work table for close to 50 years, another ended up with a loop of Z track as an Nn3 test track, and I used them over plywood for one of my permanent layout towns.
I have no idea what they're made of today, but mine is some kind of brown fibrous material, with a smooth white surface on one side.