Their CV bridge kits use the same idea - molded ties are included for bridge ties, you're to put rail down of your choice, and roll the spikes down over the base.
It 'might work'.... the plastic they use in the bridge kit is significantly softer and more flexible than typical injection styrene. I'd say it has more to do with the thickness and precision of the rail base in comparison to the height of the 'nubs' for how much grip you get. On my bridges I have to do a full-width deck with a road, so I replaced the ties with Micro-Engineering bridge flex (it doesn't have the obstruction of the longitudal stringer on top of the tie) and they use the same method - a tiny nub flared over to hold the rail base. That certainly seems to work for them.
I was ready to use the CV tie strip as intended, but I was still going to 'goo' the bottom of the rail base to make sure I had an extra level of security. If you're worried you might try that. The nice part is that you've got something there to help establish gauge.